Clinical trials, particularly randomized trials are critical in delivering reliable evidence about the efficacy of an intervention. Clinical trial data can also provide important information about the potential adverse effects of treatment. Currently, not all trials on human participants are reported in the peer-reviewed literature. PLoS Clinical Trials aims to fill this gap. As an open-access journal, all articles published in the journal will be immediately and freely available online. Join them in supporting these goals, and get your paper read by the widest possible audience: submit your trial results today.